Is CVE-2025-49220 in the CISA KEV catalog?

No. CVE-2025-49220 is not currently on the CISA Known Exploited Vulnerabilities list.

What is the CVSS severity of CVE-2025-49220?

CVE-2025-49220 has a CVSS v3 base score of 9.8 (CRITICAL).

What is the EPSS score for CVE-2025-49220?

CVE-2025-49220 has an EPSS score of 1.94% (78th percentile), estimating the probability of exploitation in the next 30 days.

How do I fix or mitigate CVE-2025-49220?

No published fix for CVE-2025-49220 has been found yet. Check the linked vendor advisories for guidance as it becomes available.

CVE & CISA-KEV Catalog

CVE-2025-49220

CRITICALEPSS 78th pctl

9.8

CVSS v3

NVD

Description

An insecure deserialization operation in Trend Micro Apex Central below version 8.0.7007 could lead to a pre-authentication remote code execution on affected installations. Note that this vulnerability is similar to CVE-2025-49219 but is in a different method.

CWE-477 CWE-502Deserialization of Untrusted Data

How to fix

No published remediation has been found for this vulnerability's affected products yet.

Mitigation guidance may be in the linked vendor advisories in the References section below.

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CVSS v3 Vector

Exploitability

Attack VectorNetwork

Attack ComplexityLow

Privileges RequiredNone

User InteractionNone

ScopeUnchanged

Impact

ConfidentialityHigh

IntegrityHigh

AvailabilityHigh

CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Exploit Intelligence

1.94%probability of exploitation in 30 days

78thpercentile

Elevated risk: more likely to be exploited than 78% of all known CVEs.

References

Vendor Advisory1

success.trendmicro.com

Third-Party Advisory1

zerodayinitiative.com

Related Vulnerabilities

Other CWE-477 vulnerabilities, ordered by exploit likelihood. View all

CVE	Severity	CVSS	EPSS	Exploited	Fix
CVE-2025-49213	Critical	9.8	9.0%	-	Fix
CVE-2025-49212	Critical	9.8	9.0%	-	Fix
CVE-2018-17890	Critical	9.8	3.3%	-	-
CVE-2019-18251	High	8.8	1.7%	-	-
CVE-2025-49219	Critical	9.8	1.3%	-	-
CVE-2025-49217	Critical	9.8	1.0%	-	Fix

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This product uses NVD data but is not endorsed or certified by the NVD. EPSS scores courtesy of FIRST.org (https://www.first.org/epss). Source: CISA KEV Catalog. Data as of 2025-09-08.