Is CVE-2025-12921 in the CISA KEV catalog?

No. CVE-2025-12921 is not currently on the CISA Known Exploited Vulnerabilities list.

What is the CVSS severity of CVE-2025-12921?

CVE-2025-12921 has a CVSS v3 base score of 4.3 (MEDIUM).

What is the EPSS score for CVE-2025-12921?

CVE-2025-12921 has an EPSS score of 0.47% (37th percentile), estimating the probability of exploitation in the next 30 days.

How do I fix or mitigate CVE-2025-12921?

No published fix for CVE-2025-12921 has been found yet. Check the linked vendor advisories for guidance as it becomes available.

CVE & CISA-KEV Catalog

CVE-2025-12921

MEDIUM

4.3

CVSS v3

NVD

Description

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

CWE-74Injection CWE-91

How to fix

No published remediation has been found for this vulnerability's affected products yet.

Mitigation guidance may be in the linked vendor advisories in the References section below.

CVSS v3 Vector

Exploitability

Attack VectorNetwork

Attack ComplexityLow

Privileges RequiredLow

User InteractionNone

ScopeUnchanged

Impact

ConfidentialityLow

IntegrityNone

AvailabilityNone

CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N

Exploit Intelligence

0.47%probability of exploitation in 30 days

37thpercentile

Low risk: more likely to be exploited than 37% of all known CVEs.

References

Exploit2

Third-Party Advisory2

VDB Entry1

vuldb.com

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This product uses NVD data but is not endorsed or certified by the NVD. EPSS scores courtesy of FIRST.org (https://www.first.org/epss). Source: CISA KEV Catalog. Data as of 2026-04-29.