Is CVE-2026-21997 in the CISA KEV catalog?

No. CVE-2026-21997 is not currently on the CISA Known Exploited Vulnerabilities list.

What is the CVSS severity of CVE-2026-21997?

CVE-2026-21997 has a CVSS v3 base score of 8.5 (HIGH).

What is the EPSS score for CVE-2026-21997?

CVE-2026-21997 has an EPSS score of 0.20% (10th percentile), estimating the probability of exploitation in the next 30 days.

How do I fix or mitigate CVE-2026-21997?

No published fix for CVE-2026-21997 has been found yet. Check the linked vendor advisories for guidance as it becomes available.

CVE & CISA-KEV Catalog

CVE-2026-21997

HIGH

8.5

CVSS v3

NVD

Description

Vulnerability in the Oracle Life Sciences Empirica Signal product of Oracle Life Science Applications (component: Common Core). Supported versions that are affected are 9.2.1-9.2.3. Easily exploitable vulnerability allows low privileged attacker with network access via HTTP to compromise Oracle Life Sciences Empirica Signal. While the vulnerability is in Oracle Life Sciences Empirica Signal, attacks may significantly impact additional products (scope change). Successful attacks of this vulnerability can result in unauthorized creation, deletion or modification access to critical data or all Oracle Life Sciences Empirica Signal accessible data as well as unauthorized read access to a subset of Oracle Life Sciences Empirica Signal accessible data. CVSS 3.1 Base Score 8.5 (Confidentiality and Integrity impacts). CVSS Vector: (CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N).

CWE-284Improper Access Control

How to fix

No published remediation has been found for this vulnerability's affected products yet.

Mitigation guidance may be in the linked vendor advisories in the References section below.

CVSS v3 Vector

Exploitability

Attack VectorNetwork

Attack ComplexityLow

Privileges RequiredLow

User InteractionNone

ScopeChanged

Impact

ConfidentialityLow

IntegrityHigh

AvailabilityNone

CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N

Exploit Intelligence

0.20%probability of exploitation in 30 days

10thpercentile

Low risk: more likely to be exploited than 10% of all known CVEs.

References

Vendor Advisory1

oracle.com

Related Vulnerabilities

Other CWE-284 (Improper Access Control) vulnerabilities, ordered by exploit likelihood. View all

CVE	Severity	CVSS	EPSS	Exploited	Fix
CVE-2023-27350	Critical	9.8	100%	KEV + Ransom	Fix
CVE-2019-1653	High	7.5	100%	KEV	-
CVE-2023-23752	Medium	5.3	100%	KEV	Fix
CVE-2023-29298	High	7.5	100%	KEV	-
CVE-2023-38205	High	7.5	100%	KEV	-
CVE-2024-27348	Critical	9.8	99%	KEV	Fix

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This product uses NVD data but is not endorsed or certified by the NVD. EPSS scores courtesy of FIRST.org (https://www.first.org/epss). Source: CISA KEV Catalog. Data as of 2026-05-01.